Nice game.
It's pretty awesome BUT I have a few complaints.
1) My 1st playthrough all airports and shipyards closed and I killed half the planet and that's it... so in my second playthrough I knew it all came down to first infect all the world and then evolve my disease.
2) Most symptoms are quite expensive and most of them are very noticeable. It would be nice if you had some kind of benefit by having more symptoms, but instead it just makes that everyone becomes aware and you can't win the game.
3) The idea that symptoms have a sell cost is not bad... but most are way too expensive, and at the rates one gets evolution points it takes quite a lot of time.
4) The game needs more speed, or some way to get evolution points faster.
5) Madagascar has only a bay! It's too difficult to get to it sometimes, because even if you have Parasite and no visibility at all, the world will at some point be aware of your disease and if you could'nt get to madagascar before they closed, you're screwed.
...Well, I think that's about it. The idea is seriously GREAT, and the implementation was quite good overall... but I think you could give it some tweaking here and there. I hope to see the 3rd one! :)